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Obesity Management During Reproductive Years
Clinical Queries: Expert Insights to Improve Obesity Management During Reproductive Years 

Released: January 20, 2026

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You review AOM options with Rita. You explain that weight loss of 5% to 10% would provide health benefits, but more weight loss will provide greater improvement in her health conditions—MASH, prediabetes, and metabolic syndrome. You also note that some AOMs are approved for treatment of conditions associated with overweight/obesity. Rita’s weight is 180 lb (82 kg) and her BMI is 34 kg/m2. She would like to bring her BMI below 30, which would require a weight loss of 22 lb (10 kg) or 12%. She previously mentioned that she is not planning to have more children.

Which AOM would you recommend as the best option for Rita based on her weight loss goal, comorbid health conditions, and life fit?