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Bridging Discoveries to Practice: CCO's Conference to Clinic Highlights From the 2025 ASH Annual Meeting *

Review certified expert analysis text modules, podcasts, and Capsule Summaries highlighting key studies from the 2025 ASH annual meeting.

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Program Content

6 Capsule Summaries

Activities

CLL17
CLL17: Phase III Trial of Continuous Ibrutinib vs Fixed-Duration Venetoclax Plus Obinutuzumab or Venetoclax Plus Ibrutinib for Untreated CLL
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 10, 2025

CaDAnCe 101
CaDAnCe-101 Update: Phase I Study Evaluating BTK Degrader BGB-16673 in R/R CLL/SLL
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 11, 2025

Sonrotoclax RR MCL
Phase I/II Trial of Sonrotoclax (BGB-11417) in R/R Mantle Cell Lymphoma After Prior BTK Inhibitor Therapy 
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 11, 2025

BRUIN CLL 314
BRUIN CLL-314: Pirtobrutinib vs Ibrutinib in Treatment-Naive and BTKi-Naive R/R CLL/SLL
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

Surovatamig RR FL
Phase I Trial of CD19 x CD3 T-Cell Engager Surovatamig (AZD0486) in R/R Follicular Lymphoma: 3-Yr Follow-up
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

BRUIN CLL 313
BRUIN CLL-313: Pirtobrutinib vs Bendamustine + Rituximab in Treatment-Naive CLL/SLL
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

Activities

PulseCast Lymphomas ASH 2025
PulseCast: Highlights in Lymphomas From the 2025 ASH Annual Meeting
Podcast Episodes
Congratulations: You achieved a completion on 04/09/2022

Released: December 19, 2025

6 Capsule Summaries

Activities

SAVE Trial
SAVE: Phase I/II Study of Oral Revumenib Plus Decitabine/Cedazuridine and Venetoclax in Cohort of Patients with Newly Diagnosed AML
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 08, 2025

ASC2ESCALATE
ASC2ESCALATE: Asciminib in Patients With Chronic-Phase CML After 1 Prior TKI
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 11, 2025

VICEROY
VICEROY: Venetoclax + Azacitidine + Gilteritinib in Patients With ND FLT3-Mutated AML Ineligible for Intensive Induction Chemotherapy
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

PARADIGM
PARADIGM: Randomized Phase II Trial of Azacitidine + Venetoclax vs Conventional Intensive Chemotherapy for Fit Patients With Newly Diagnosed AML
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

FASCINATION
Phase II FASCINATION: 3-Yr Update of Asciminib + Conventional BCR::ABL1 Inhibitors in Newly Diagnosed CML
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

KOMET 007
KOMET-007: Phase Ib Study of Ziftomenib + Venetoclax/Azacitidine in Newly Diagnosed NPM1-Mutated Acute Myeloid Leukemia
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 16, 2025

Activities

PulseCast Leukemias ASH 2025
PulseCast: Highlights in Leukemias From the 2025 ASH Annual Meeting
Podcast Episodes
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2025

7 Capsule Summaries

Activities

DURGA 1
DURGA-1: Phase Ib/II Study of AZD0120, a BCMA/CD19 Dual-Targeting CAR T-Cell Therapy, in R/R MM
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 09, 2025

CAMMA 1 Updated Analysis
CAMMA 1: Updated Safety, Efficacy, and Biomarker Analyses From Phase I Study of Cevostamab + Pomalidomide + Dexamethasone in BCMA1-Naive RRMM
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 09, 2025

Cilta cel for Standard Risk RRMM
Extended Efficacy and Safety Outcomes With Ciltacabtagene Autoleucel (Cilta-cel) in Patients With R/R MM With Standard-Risk Cytogenetics
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 09, 2025

Cevostamab Consolidation in RR MM
Phase II Trial of Cevostamab Consolidation After Anti-BCMA CAR T-Cell Therapy in R/R MM
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 10, 2025

iMMagine 1
iMMagine-1 Update: Phase II Study of D-Domain BCMA-Directed CAR T-Cell Therapy, Anitocabtagene Autoleucel, in R/R MM
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 10, 2025

RedirecTT 1 Update
RedirecTT-1 Update: Talquetamab + Teclistamab in Relapsed/Refractory MM With Extramedullary Disease
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

MajesTEC3
MajesTEC-3: Teclistamab + Daratumumab vs Daratumumab-Based Regimens (DPd/DVd) in Patients With R/R Multiple Myeloma
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

Activities

PulseCast Multiple Myeloma ASH 2025
PulseCast: Highlights in Multiple Myeloma From the 2025 ASH Annual Meeting
Podcast Episodes
Congratulations: You achieved a completion on 04/09/2022

Released: December 23, 2025

6 Capsule Summaries

Activities

INCA033989 in ET
Phase I Trial of INCA033989, a First-in-Class Antibody Targeting Mutant Calreticulin: Safety and Efficacy in Essential Thrombocythemia
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 09, 2025

IMerge Post Hoc Analysis
IMerge Post Hoc Analysis: Treatment-Emergent Cytopenias and Response With Imetelstat in Patients With Lower-Risk MDS
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 10, 2025

VERONA Subgroup Analyses
VERONA: Subgroup Analyses of Venetoclax or Placebo Combined With Azacitidine in Treatment-Naive Higher-Risk MDS
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 10, 2025

INCA033989 in MF
Preliminary Results From 2 Phase I Trials Exploring the Mutant Calreticulin-Specific mAb INCA033989 ± Ruxolitinib in Patients With MF
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 11, 2025

MANIFEST 2 96 Wk Update
MANIFEST-2 96-Wk Update: Ruxolitinib + Pelabresib or Placebo in Patients With JAK Inhibitor–Naive MF
Case Challenge
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

Reduced Duration HMA in LR MDS
Randomized Phase II Trial of Reduced Treatment Durations With Hypomethylating Agents in Lower-Risk MDS
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 17, 2025

Activities

PulseCast MDS MPNs ASH 2025
PulseCast: Highlights in MDS/MPNs From the 2025 ASH Annual Meeting
Podcast Episodes
Congratulations: You achieved a completion on 04/09/2022

Released: December 30, 2025

5 Capsule Summaries

Activities

VAYHIT3
VAYHIT3: Secondary Analysis of Phase II Trial of Ianalumab in Patients With Previously Treated Primary ITP
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

VAYHIT2
VAYHIT2: Phase III Trial of Eltrombopag ± Ianalumab, an Anti-BAFF Receptor Monoclonal Antibody, as Second-line Therapy for Primary ITP
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 12, 2025

VIVID 3
VIVID 3: Phase I/II Study of VGA039, a Novel Protein S Antibody, as Maintenance Therapy in Patients With von Willebrand Disease
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 15, 2025

RWE of IV Iron in IDA
Real-world Evidence Study of IV Iron Use During Acute Infection in Patients With Iron Deficiency Anemia
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 16, 2025

ICI ITP
Multicenter Cohort Study of ICI-Associated Immune Thrombocytopenia Incidence and Outcomes in Adults Receiving Care at US Academic Centers
Conference Coverage
Slideset
Congratulations: You achieved a completion on 04/09/2022

Released: December 16, 2025

Activities

PulseCast Nonmalignant Disorders ASH 2025
PulseCast: Highlights in Nonmalignant Blood Disorders From the 2025 ASH Annual Meeting
Podcast Episodes
Congratulations: You achieved a completion on 04/09/2022

Released: December 18, 2025

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Supported by educational grants from AstraZeneca, BeOne Medicines, Genentech, Geron Corporation, Incyte, Johnson & Johnson, Lilly, and Novartis Pharmaceuticals Corporation.

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Johnson & Johnson

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Novartis Pharmaceuticals Corporation

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*Decera Clinical Education is an independent medical education company that provides state-of-the-art medical information to healthcare professionals through conference coverage and other educational programs.