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HER2 Positive GEA and BTC IDST
Interactive Decision Support Tool: HER2-Positive GEA and BTC Treatment Guidance

Released: April 24, 2026

Instructions

This Interactive Decision Support Tool provides treatment recommendations from 5 experts based on the specific patient and disease characteristics you enter in the tool. It is recommended that you have as much information as possible available before you begin.

You will be prompted to provide specific information about your patient including treatment setting, performance status, biomarker status, treatment history, and specific comorbidities, such as organ function, presence or risk of developing autoimmune disease, and presence of cardiac or pulmonary dysfunction.

Click on your selections. Your choices can be changed at any time simply by selecting the [change] icon by the question you want to change and entering a new choice.

Additional information on each variable/characteristic and why it is important for making management decisions is available by clicking on the [i] icon after each selection.

When all patient characteristics are entered, you will be asked to select the management option you are currently planning. Once that information is entered, you can click on Submit Patient Case to view the expert recommendations.

After reviewing your case-specific recommendations, you will be asked brief questions about how the recommendations influenced your decision-making. You will then be able to enter a new case scenario by clicking the Start New Case button.

When viewing the tool on the Decera Clinical Education Web site, you will also have the following options:

  • Print/download the recommendations along with a summary of the patient characteristics and selected therapy you entered by clicking the Case Summary button.
  • View an Additional Considerations section covering additional factors that may affect choice of therapy in GEA and BTC and future directions in the management of these diseases.

Access to and use of this Interactive Decision Support Tool titled, “Interactive Decision Support Tool: HER2-Positive GEA and BTC Treatment Guidance” is provided subject to the following terms and conditions. PLEASE READ THESE TERMS CAREFULLY.

This Interactive Decision Support Tool is designed to educate healthcare professionals on making optimal management choices for monitoring or treating individuals with HER2-positive advanced GEA and BTC. The information provided is based on guideline recommendations and expert guidance of Richard Kim, MD; Geoffrey Ku, MD; Amit Mahipal, MD, MPH; Shubham Pant, MD; and Rachna T. Shroff, MD, MS, FASCO.

The material published by Decera Clinical Education reflects the views of the reviewers or authors of the material, not those of Decera Clinical Education, the accredited provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the FDA. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Although the information contained in the “Interactive Decision Support Tool: HER2-Positive GEA and BTC Treatment Guidance” has been produced and processed from sources believed to be reliable, no warranty, expressed or implied, is made regarding the accuracy, adequacy, completeness, legality, reliability, or usefulness of any information. This disclaimer applies to both the isolated and aggregate uses of the information. Decera Clinical Education provides this information on an as-is basis. This disclaimer applies to all material published by Decera Clinical Education including but not limited to medical information or opinions. All warranties of any kind, expressed or implied, including but not limited to the implied warranties of merchantability, fitness for a particular purpose, freedom from contamination by computer viruses, and noninfringement of proprietary rights are disclaimed.

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© 2026 Decera Clinical Education. All rights reserved.

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