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Obesity phenotypes and AOM strategies

CE / CME

Obesity Management Strategies for Patients With Suboptimal or No Response to Antiobesity Medications

Physician Assistants/Physician Associates: 0.25 AAPA Category 1 CME credit

Nurse Practitioners/Nurses: 0.25 Nursing contact hour

Physicians: maximum of 0.25 AMA PRA Category 1 Credit

Released: September 30, 2025

Expiration: September 29, 2026

Activity

Progress
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Course Completed

Introduction

In this module, Donna H. Ryan, MD, discusses the phenotypes of obesity, how these are changing the obesity treatment paradigm in developing patient-centered treatment plans, and best practices for managing patients with suboptimal or no response to antiobesity medications (AOMs).

The key points discussed in this module are illustrated with thumbnails from the accompanying downloadable PowerPoint slidesets, which can be downloaded here or by clicking any of the slide thumbnails in the module alongside the expert commentary.

Clinical Care Options plans to measure the educational impact of this activity. Some questions will be asked twice: once at the beginning of the activity and then once again after the discussion that informs the best choice. Your responses will be aggregated for analysis, and your specific responses will not be shared. 

Before continuing with this educational activity, please take a moment to answer the following questions.

A 38-year-old woman with class III obesity (BMI 42 kg/m²) reports constant hunger, especially in the evening, and frequent emotional eating. She has no history of diabetes or cardiovascular disease. Her goal is to feel more in control of her appetite. Which antiobesity medication is most likely to assist with reward-related eating and cravings?

How many people with obesity do you provide care for in a typical week?

For those who practice in academic or community settings, please indicate your practice setting: