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Two Drugs or Three? Navigating the Latest Evidence for Oral ART Initiation

For decades, 3-drug regimens (3DRs) were considered the “gold standard” of antiretroviral therapy for HIV. However, numerous clinical trials and real-world studies demonstrated that modern 2-drug regimens (2DRs), both oral and long-acting injectable, are noninferior to 3DR alternatives. In this live webinar, expert faculty share practical frameworks and evidence to help you make confident, individualized decisions between 2- and 3-drug regimens when initiating antiretroviral therapy.

  ACPE
  | AMA
  | ANCC
Who Should Attend

This activity is intended for physicians (including HIV/infectious disease specialists, primary care physicians, and internists), nurse practitioners, pharmacists, and other healthcare professionals involved in the initiation of antiretroviral therapy in adults living with HIV.

All Events

Two Drugs or Three? Navigating the Latest Evidence for Oral ART Initiation

Upcoming Events

September

17

2026

12:00 PM - 1:30 PM Eastern Time (ET)

Virtual

September

29

2026

12:30 PM - 2:00 PM Eastern Time (ET)

Virtual

Topics

HIV

Additional Info

There are no fees required to participate in this activity.

Americans With Disabilities Act 
Event staff will be glad to assist you with any special needs (eg, physical, dietary). Please contact customer support prior to the live event.

CME/CE Info

Goal Statement
The goal of this activity is to equip healthcare professionals with the evidence and individualized decision-making frameworks needed to select confidently between 2-drug and 3-drug antiretroviral regimens when initiating ART.

Target Audience
This activity is intended for physicians (including HIV/infectious disease specialists, primary care physicians, and internists), nurse practitioners, pharmacists, and other healthcare professionals involved in the initiation of antiretroviral therapy in adults living with HIV.

Learning Objectives
Upon completion of this event, participants should be able to:

  • Integrate the clinical evidence, including results from VOGUE and other key trials and real-world studies, to make informed, evidence-based decisions about the comparative merits of 2DR and 3DR for ART initiation
  • Apply evidence-based clinical frameworks to select between 2DR and 3DR across a range of commonly encountered first-line ART scenarios, and communicate the rationale for 2DR confidently in shared decision-making conversations with patients

Accreditation

Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC dba Decera Clinical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

Clinical Care Options, LLC dba Decera Clinical Education designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1.5 contact hours.

Continuing Pharmacy Education

Clinical Care Options, LLC dba Decera Clinical Education designates this continuing education activity for 1.5 contact hours (0.15 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number: Specific to each date.

Type of Activity: Application

Upon successfully completing the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.

IPCE Credit Designation

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This activity was planned by and for the healthcare team, and learners will receive 1.5 Interprofessional Continuing Education (IPCE) credits for learning and change.

CME Passport

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The CME credits that physicians earn from this activity will be submitted to ACCME's CME Passport, a free, centralized web application where you can create a personalized account to view, track, and generate transcripts of your reported CME credit. Visit www.cmepassport.org to create your account.

Disclosure of Conflicts of Interest
Decera Clinical Education requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to Decera Clinical Education policy. Decera Clinical Education is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

Acknowledgement

Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

Clinical Care Options, LLC dba Decera Clinical Education

Supporters

This activity is supported by an educational grant from ViiV Healthcare.

ViiV Healthcare

For customer support please click here.

Mailing Address:

 

Decera Clinical
12001 Sunrise Valley Drive
Suite 304
Reston, VA 20191