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ARIA Training Module
Spot the Signal: Global Radiology Training for ARIA Detection in Alzheimer’s Care

Released: April 23, 2026

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Case 1: Detection of ARIA-E

Dr Lövblad:

The prior MRI, which is in the lower row, is normal. With the help of the arrows, it is very clear on the follow-up scans that now there are ARIA-E both frontally and in the occipital region. The next step would then be to grade it and determine whether the patient has symptoms.

Dr Benzinger:

This is the tricky part because overall, we might think it looks mild. But in fact, if you have 2 separate regions of the brain, as in this case, frontal and occipital, automatically it becomes moderate according to the grading classification.

This example illustrates that visual impression alone may be misleading; radiologists must apply the formal grading scale rather than relying on subjective assessments of what appears “mild” or “moderate.”

Would you report ARIA-H for this patient?