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Beyond Hot Flashes: Recognizing and Managing Mood Disorders During Perimenopause

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Released: September 21, 2026

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Perimenopause is associated with a 2- to 4-fold increased risk of depression compared with other life periods, highlighting the importance of recognizing mood symptoms during this hormonal transition. This downloadable slideset examines hormonal fluctuations, vasomotor and sleep symptoms, and patient-specific risk factors that may contribute to perimenopausal depression. It also reviews current approaches to management, including antidepressants, hormone replacement therapy, nonhormonal options, and lifestyle strategies.

Perimenopause and Mood Disorders

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Released: September 21, 2026