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Optimizing Oral Targeted Therapies for HR+/HER2- Breast Cancer

Podcast

Oral targeted therapies are increasingly used across early-stage and metastatic HR-positive/HER2-negative breast cancer, but optimal use can be complicated by disease setting, biomarker results, prior therapy, tolerability concerns, and adherence needs. In this podcast, expert faculty discuss current evidence and practical strategies for selecting and sequencing oral targeted therapies, applying biomarker-informed decision-making, monitoring and managing adverse events, and using pharmacist-led approaches to support adherence and long-term treatment persistence.

Released: August 14, 2026

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Provided by ProCE, LLC.

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Supporters

Supported by an educational grant from AstraZeneca.

AstraZeneca

Target Audience

This activity has been designed to meet the educational needs of oncology pharmacists and other healthcare professionals caring for patients with breast cancer.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Apply the latest safety and efficacy evidence for oral targeted therapies to clinical practice to individualize the management of patients with HR-positive/HER2-negative breast cancer

  • Collaborate with patients, caregivers, and the multidisciplinary team to use evidence-based approaches for monitoring and managing adverse events associated with oral targeted therapies for HR-positive/HER2-negative breast cancer

  • Support adherence/persistence to oral targeted therapies in patients with HR-positive/HER2-negative breast cancer through expert-recommended communication strategies, tools, and resources

Financial Disclosures

Primary Author

Jordan Hill, PharmD, BCOP, has no relevant financial relationships to disclose.

Danielle Roman, PharmD, BCOP: consultant/advisor/speaker: Daiichi Sankyo, Genentech, Pfizer, Regeneron.

Additional Disclosures

Generative artificial intelligence (AI) tools were used for revising or refining educational content and drafting assessment question(s) and/or rationale(s). All AI-assisted content underwent human review, editing, and validation by qualified faculty and accredited education staff to ensure scientific accuracy, balance, and compliance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.