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To Stop or Not to Stop? Real-world Deprescribing Dilemmas

Slideset

Psychotropic deprescribing is not simply about reducing medication burden, but about reassessing whether each treatment continues to provide meaningful benefit for the individual patient. This downloadable slideset uses real-world clinical dilemmas to examine when deprescribing, continuation, or optimization may be appropriate. It also highlights strategies for individualized risk–benefit assessment, shared decision-making, tapering, and follow-up for withdrawal or symptom recurrence.

Released: September 22, 2026

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Faculty

Joseph F. Goldberg

Joseph F. Goldberg, MD

Clinical Professor of Psychiatry
Icahn School of Medicine at Mount Sinai
New York, New York
Lisa M. Harding

Lisa M. Harding, MD

Medical Director
Mood Institute
Assistant Clinical Professor of Psychiatry
Yale School of Medicine
New Haven, Connecticut

Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Target Audience

This activity is intended for physicians, nurse practitioners, registered nurses, pharmacists, physician associates, social workers, and psychologists engaged in the care of patients with mood disorders.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Identify clinical circumstances in which psychotropic deprescribing should be considered based on current consensus recommendations

  • Apply individualized risk-benefit assessment, adherence evaluation, and shared decision-making when considering psychotropic deprescribing

  • Differentiate situations in which medication discontinuation or simplification is appropriate from those in which continuation, optimization, or adverse effect management may be preferable

Additional Disclosures

Generative artificial intelligence (AI) tools were used for drafting educational content and revising or refining educational content. All AI-assisted content underwent human review, editing, and validation by qualified faculty and accredited education staff to ensure scientific accuracy, balance, and compliance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.