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The “Golden Hour” in HIV Prevention: Why It’s Time for Same-Day HIV PrEP 

Clinical Thought

This principle of offering and receiving an intervention on the same day has been successfully used to improve uptake, access, and coverage of other preventive health measures such as immunizations. Why should HIV PrEP be any different?

Released: May 18, 2026

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Supporters

Supported by an educational grant from Gilead Sciences, Inc.

Gilead Sciences, Inc.

Target Audience

This program is intended for physicians, pharmacists, registered nurses, and other healthcare professionals (both specialists and generalists) who provide PrEP.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Apply current IAS-USA and CDC guideline recommendations to determine when rapid or same-day PrEP is appropriate

  • Implement efficient, safe, and sustainable clinical workflows that support same‑day PrEP initiation across varied practice settings

  • Individualize the choice of PrEP modality—oral or long‑acting injectable—during same‑day clinical encounters

Disclosure

Primary Author

Jeffrey Kwong, DNP, MPH, AGPCNP-BC, FAANP, FAAN, AAHIVS, ACRN, has no relevant financial relationships to disclose.