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Decision Support Summary: Initial Oral ART With 2DR vs 3DR by Clinical Scenario

When can 2-drug regimens (2DRs) vs 3-drug regimens (3DRs) be considered for initial ART? In many scenarios, modern 2DRs are noninferior to 3DR alternatives. This reference reviews key clinical scenarios and outlines when to consider one vs the other.

Comparing 2DR and 3DR