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The Near Future of Regimen Simplification for Heavily Treatment–Experienced HIV

Clinical Thought

Recent data highlighted the efficacy and safety of several new agents in the pipeline that may offer heavily treatment–experienced people an opportunity for clinically meaningful regimen optimization. Here are our thoughts on how they may change the landscape of HIV treatment.

Released: April 28, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by an educational grant from ViiV Healthcare.

ViiV Healthcare

Target Audience

This activity is intended for physicians, pharmacists, and other healthcare professionals involved in the care of people living with HIV.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Devise antiretroviral treatment strategies for people with multidrug-resistant HIV that leverage the attributes of agents approved for use in this setting

Disclosure

Primary Author

Charlotte-Paige Rolle, MD, MPH: consultant/advisor/speaker: Gilead, ViiV; researcher: Gilead, Merck Sharp & Dohme, ViiV.

Paul E. Sax, MD: consultant/advisor/speaker: Gilead, Merck, ViiV; researcher: Gilead, ViiV.