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PBC Pruritus and Fatigue Symptoms

CE / CME

Management of PBC Pruritus and Fatigue Symptoms

Pharmacists: 0.75 contact hour (0.075 CEUs)

Physicians: maximum of 0.75 AMA PRA Category 1 Credit

Nurse Practitioners/Nurses: 0.75 Nursing contact hour

Released: March 18, 2026

Expiration: March 17, 2027

Activity

Progress
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Course Completed

Introduction

In this module, Aliya Gulamhusein, MD, MPH, FRCPC, discusses evaluation, monitoring, and management of the primary biliary cholangitis (PBC) symptoms of pruritus and fatigue.

The key points discussed in this module are illustrated with thumbnails from the accompanying downloadable PowerPoint slideset, which can be found here or downloaded by clicking on any of the slide thumbnails in the module alongside the expert commentary.

Before continuing with this educational activity, please take a moment to answer the following questions.

How many people with PBC do you provide care for in a typical month?

For those who practice in academic or community settings, please indicate your practice setting:

If you practice in gastroenterology, is hepatology your specialty?

A woman with PBC returns for follow-up after 6 months of ursodeoxycholic acid (UDCA). Her alkaline phosphatase (ALP) is 1.5 time the upper limit of normal, total bilirubin is normal, and she has not reported any symptoms. Which is the most appropriate next step regarding pruritus assessment?

A woman with PBC has been receiving UDCA for 12 months. She reports that she cannot get through the day without resting and is struggling to function at work. What is the most appropriate next step in management?