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Beyond cBTKi Progression in R/R MCL: Mechanism-Based Sequencing and Community Implementation

As covalent BTK inhibitors have moved into the first-line setting for MCL, options for relapsed/refractory disease have also expanded to include a variety of BCL2i-based therapies, CAR T-cell therapies, and bispecific antibodies. Join this webinar for expert insight into the complex patient, disease, and prior treatment factors that inform treatment selection for R/R MCL.

  AAPA
  | ACPE
  | AMA
  | ANCC
Who Should Attend

This activity is intended for hematologist/oncologists, nurse practitioners, physician associates, nurses, pharmacists, and other interprofessional team members involved in the care of patients with R/R MCL.

All Events

Beyond cBTKi Progression in R/R MCL: Mechanism-Based Sequencing and Community Implementation

Upcoming Events

November

09

2026

3:30 PM - 4:30 PM Eastern Time (ET)

Virtual

Topics

R/R mantle cell lymphoma
B-cell lymphoma

Additional Info

There are no fees required to participate in this activity.

Americans With Disabilities Act
Event staff will be glad to assist you with any special needs (eg, physical, dietary). Please contact Customer Support prior to the live event.

CME/CE Info

Goal Statement
To improve learners’ knowledge, confidence, and competence in evidence-informed, patient-centered selection and implementation of post-cBTKi therapy options for patients with R/R MCL by strengthening mechanism-based sequencing, safety mitigation, community referral workflows, and interprofessional care coordination.

Target Audience
This activity is intended for hematologist/oncologists, nurse practitioners, physician associates, nurses, pharmacists, and other interprofessional team members involved in the care of patients with R/R MCL.

Learning Objectives
Upon completion of this activity, participants should be able to:

  • Evaluate patient-, disease-, and prior-treatment factors that inform post-cBTKi therapy selection in R/R MCL, including BTKi progression vs intolerance, relapse tempo, tumor burden, TP53 mutation, blastoid/pleomorphic morphology, Ki-67, performance status, comorbidities, access, and patient goals

  • Compare BTK- and BCL2-directed small-molecule strategies and contextualize CAR T-cell and bispecific antibody options using mechanism, efficacy, safety, treatment duration, monitoring needs, and implementation feasibility

  • Apply best practices for therapy-specific safety planning and supportive care, with emphasis on TLS risk assessment and monitoring for BCL2 inhibitor-based therapy, infection/cytopenia mitigation, drug interactions, referral readiness, and patient/caregiver counseling

  • Implement interprofessional, community-relevant care pathways that improve referral timing, shared decision-making, patient/caregiver education, monitoring adherence, and reassessment for patients with R/R MCL after cBTKi exposure

Accreditation

Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC dba Decera Clinical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Physician Continuing Medical Education

Clinical Care Options, LLC dba Decera Clinical Education designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1.0 contact hour.

Continuing Pharmacy Education

Clinical Care Options, LLC dba Decera Clinical Education designates this continuing education activity for 1.0 contact hour (0.10 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number: JA4008176-0000-26-586-L01-P

Type of Activity: Application 

Upon successfully completing the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.

Physician Associate Continuing Medical Education

Clinical Care Options, LLC dba Decera Clinical Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit. PAs should only claim commensurate with the extent of their participation.

American Board of Internal Medicine Maintenance of Certification

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Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 1.0 MOC point in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABIM MOC credit.

For ABIM MOC points, your information will be shared with the ABIM through Decera Clinical Education’s Joint Accreditation Program and Activity Reporting System (JAPARS). Please allow 6-8 weeks for your MOC points to appear on your ABIM records.

By sharing your Diplomate Board ID # and DOB, you are giving Decera Clinical Education permission to use this information/data to report your participation to these Boards via the Joint Accreditation Program and Activity Reporting System (JA-PARS).

IPCE Credit Designation

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This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credit for learning and change.

CME Passport

The CME credits that physicians earn from this activity will be submitted to ACCME's CME Passport, a free, centralized web application where you can create a personalized account to view, track, and generate transcripts of your reported CME credit. Visit www.cmepassport.org to create your account.

Disclosure of Conflicts of Interest
Decera Clinical Education requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to Decera Clinical Education policy. Decera Clinical Education is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

Acknowledgement

Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

Clinical Care Options, LLC dba Decera Clinical Education

Supporters

This activity is supported by an educational grant from BeOne Medicines.

BeOne Medicines

For customer support please click here.

Mailing Address:

 

Decera Clinical Education
12001 Sunrise Valley Drive
Suite 304
Reston, VA 20191