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Major Depressive Disorder Across the Lifespan: Practical Pearls From General, Pediatric, and Geriatric Psychiatry

Slideset

Major depressive disorder presents distinct challenges across pediatric, adult, and geriatric populations, particularly when symptoms persist despite initial treatment. These downloadable slides explore age-specific approaches to screening, diagnosis, and treatment selection, with an emphasis on clinical decisions about switching antidepressants or initiating adjunctive therapies. Learners will examine emerging evidence, pharmacologic and nonpharmacologic treatment options, and practical considerations for managing residual symptoms, treatment resistance, and medication safety across the lifespan.

Released: October 21, 2026

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Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

This activity is supported by an educational grant from Intra-Cellular Therapies, Inc.

Intra-Cellular Therapies, Inc.

Target Audience

This activity is intended for healthcare professionals caring for patients with major depressive disorder, including physicians (psychiatrists and family medicine/primary care), nurse practitioners, physician associates, registered nurses, pharmacists, and psychologists.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Assess optimal timing and clinical rationale for switching or augmenting treatment in patients with MDD

  • Evaluate the pharmacologic profiles, efficacy, and safety of approved adjunctive therapies for adults with MDD that improve residual symptoms, including anhedonia and cognitive impairment

  • Apply current guideline- and evidence-based strategies to optimize dosing and titration of adjunctive therapies for adults with MDD who exhibit residual symptoms

  • Implement strategies for optimizing the management of persistent symptoms for complex or special populations with MDD to optimize long-term outcomes and functional recovery

Additional Disclosures

Generative artificial intelligence (AI) tools were used for revising or refining educational content. All AI-assisted content underwent human review, editing, and validation by qualified faculty and accredited education staff to ensure scientific accuracy, balance, and compliance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.