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Systemic Therapy Beyond HER2-Positive Disease and Multidisciplinary CNS Management

Explore systemic therapy and CNS management of breast cancer brain metastases beyond HER2-positive disease, including evidence for antibody–drug conjugates (ADCs) in metastatic triple-negative and HR-positive/HER2-negative breast cancer. Review ADC-associated adverse event management, ongoing clinical trials, and the role of brain MRI in evaluating suspected progression and treatment-related changes.

Tx Beyond HER2Pos Breast Cancer Brain Mets

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Released: November 11, 2026