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TROP2-Directed ADCs in mTNBC: Sequencing and Supportive Care

Slideset

Review key slides on the evolving role of TROP2-directed antibodydrug conjugates (ADCs) in metastatic triple-negative breast cancer (mTNBC), with a focus on evidence guiding treatment selection and sequencing, emerging strategies for sequential ADC use, and practical approaches for preventing and managing treatment-related adverse events such as neutropenia, diarrhea, oral mucositis/stomatitis, ocular toxicities, and ILD/pneumonitisThe activity also highlights how biomarker status, prior therapy, toxicity profiles, and access-related factors influence individualized treatment decisions in clinical practice.

Released: September 18, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education.

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Supporters

Supported by an educational grant from Gilead Sciences, Inc.

Gilead Sciences, Inc.

Target Audience

This activity has been designed to meet the educational needs of oncologists and other healthcare professionals involved in the management of patients with triple-negative breast cancer.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Understand the significance of TROP-2 expression in TNBC and its association with disease progression and prognosis

  • Develop treatment plans that incorporate TROP-2-directed ADCs for patients with mTNBC in alignment with current evidence and guideline recommendations

  • Evaluate pivotal clinical trial efficacy and safety data for current and emerging TROP-2-directed therapies and combinations in mTNBC

Additional Disclosures

Generative artificial intelligence (AI) tools were used for data analysis or summarization influencing content. All AI-assisted content underwent human review, editing, and validation by qualified faculty and accredited education staff to ensure scientific accuracy, balance, and compliance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.