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Translating Discoveries Into Clinical Practice to Advance the Care of Patients With Cutaneous Squamous Cell Carcinoma

Slideset

This downloadable slideset summarizes key updates in systemic therapy, surgical considerations, and multidisciplinary management strategies for cutaneous squamous cell carcinoma (cSCC).

Released: January 26, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by an educational grant from Regeneron Pharmaceuticals, Inc.

Regeneron Pharmaceuticals, Inc

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Optimize the integration of adjuvant ICI therapy into treatment plans for high-risk cSCC patients based on current guidelines and trial data

  • Refine evidence-based patient selection criteria for ICI treatment in cSCC, emphasizing clinical risk factors over PD-L1 expression

  • Proactively monitor patients receiving ICI therapy to promptly identify and manage immunotherapy-associated toxicities

  • Develop a multidisciplinary evaluation strategy for considering neoadjuvant ICI in locally advanced cSCC cases

  • Implement evidence-based, patient-centered treatment plans for advanced cSCC populations by integrating novel therapeutic strategies such as radiation-immunotherapy sequencing and intralesional therapies