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Optimizing Therapy in Relapsed/Refractory Multiple Myeloma

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An interactive clinical decision support tool designed to help hematology and oncology professionals optimize therapy in relapsed/refractory multiple myeloma. This resource integrates pivotal trial data, expert insights, and patient-centered strategies to support personalized, evidence-based care across practice settings.

Released: August 07, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical in partnership with Smart Patients.

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Supporters

Supported by an educational grant from Pfizer Inc.

Pfizer Inc.

Partners

Smart Patients

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Target Audience

This activity is intended for hematologists/oncologists, oncology nurses and nurse practitioners, physician assistants, pharmacists and other healthcare professionals involved in the care and treatment of patients with RRMM.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Interpret pivotal clinical trial data on BCMA bispecific antibodies, including efficacy, safety, and use in earlier lines of therapy

  • Apply evidence-based strategies to initiate BCMA BsAb therapy and monitor for key adverse events (eg, CRS, ICANS, infections) across diverse practice settings

  • Design multidisciplinary care coordination strategies to support therapy adherence and treatment continuation in patients transitioning from academic to community settings

  • Integrate patient education and shared decision-making tools to align treatment with patient goals and improve persistence

Financial Disclosures

Primary Author

Natalie S. Callander, MD, has no relevant financial relationships to disclose.

Sarah A. Holstein, MD, PhD: researcher (paid to institution): Bristol Myers Squibb.

Carol Ann Huff, MD: consultant/advisor/speaker: Johnson & Johnson, Prothena, Sanofi; researcher: Johnson & Johnson, Prothena.

Shaji Kumar, MD: consultant: AbbVie, Amgen, ArcellX, Beigene, BD Biosciences, Bristol Myers Squibb, Carsgen, CVS Caremark, GSK, Janssen, K36, Moderna, Pfizer, Regeneron, Roche/Genentech, Sanofi, Takeda; researcher (paid to institution): AbbVie, Amgen, AstraZeneca, Bristol Myers Squibb, Carsgen, Gracell Bio, GSK, Janssen, Oricell, Roche/Genentech, Sanofi, Takeda, Telogenomics.

Sagar Lonial, MD, FACP: consultant/advisor/speaker: Janssen, Pfizer, Regeneron; researcher: Bristol Myers Squibb, Janssen, Novartis, Takeda; other financial or material support: TG Therapeutics; individual publicly traded stock/stock options: TG Therapeutics.