Faculty

Allison Betof, MD, PhD, FASCO

Associate Professor of Medicine (Oncology)
Mark and Mary Stevens Endowed Scholar in Melanoma
Director, Solid Tumor Cellular Therapy
Stanford University School of Medicine
Stanford, California

Ahmad Tarhini, MD, PhD

Senior Member, Cutaneous Oncology & Immunology
Director, Cutaneous Clinical and Translational Research
H. Lee Moffitt Cancer Center & Research Institute
Professor, Oncologic Sciences
University of South Florida Morsani College of Medicine
Chair, SITC Global Access & Impact Committee
Chair, ORIEN Scientific Committee & Immuno Oncology Research Committee
Tampa, Florida

Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education.

Supporters

This activity is supported by an educational grant from Merck Sharp & Dohme LLC.

Merck Sharp & Dohme, LLC

Target Audience

Oncologists, nurse practitioners, physician associates, pharmacists, nurses, and other HCPs caring for patients with melanoma.

Learning Objectives

Upon completion of this activity, participants should be able to:

Integrate neoadjuvant and adjuvant immunotherapy strategies for patients with resectable melanoma into clinical practice, utilizing recent data and standardized pathologic response assessments to guide perioperative decision-making
Evaluate the clinical efficacy and logistical requirements of individualized neoantigen therapy for high-risk resected melanoma, including the importance of high-quality tissue preparation by pathologists and managing patients while waiting for personalized therapy to be manufactured
Formulate evidence-based immunotherapy treatment plans for unresectable or metastatic melanoma, including patients demonstrating primary or secondary resistance to PD-1-targeted immunotherapy
Implement standardized multidisciplinary protocols for the early recognition and management of high-grade and chronic immune-related adverse events associated with melanoma immunotherapy

Additional Disclosures

Generative artificial intelligence (AI) tools were used for data analysis or summarization influencing content, drafting educational content, revising or refining educational content, generating clinical case(s) or scenario(s), and drafting assessment question(s) and/or rationale(s). All AI-assisted content underwent human review, editing, and validation by qualified faculty and accredited education staff to ensure scientific accuracy, balance, and compliance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.

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Precision, Timing, and Teamwork in Melanoma Immunotherapy: Practical Strategies for Resectable and Metastatic Disease