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HORIZON-CRC01: Phase III Trial of Trastuzumab Rezetecan vs SoC in Chemorefractory, HER2+ Advanced CRC

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Slideset

Results from the phase III HORIZON-CRC01 trial showed clinically meaningful and statistically significant improvements in progression-free survival with the use of trastuzumab rezetecan compared with standard-of-care therapy for patients with chemorefractory, HER2-positive advanced colorectal cancer.

Released: June 16, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

This activity is supported by an educational grant from Incyte Corporation.

Incyte Corporation

Lilly

PharmaMar

Stemline Therapeutics, Inc.

Target Audience

This activity is intended for oncologists and other healthcare professionals who care for patients with various forms of gastrointestinal cancer. 

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Integrate cutting-edge data from gastrointestinal cancer studies at ASCO 2026 and expert guidance to optimize patient selection, sequencing, and monitoring across major gastrointestinal malignancies

  • Utilize prognostic and predictive biomarkers to accurately identify gastrointestinal cancer patients most likely to benefit from specific targeted therapies and treatment strategies

  • Interpret newly released clinical data on novel agents, updated guidelines, and emerging therapeutic approaches for gastrointestinal cancer to accelerate their effective incorporation into clinical practice