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EPO-PRETAR: Final Results With Early vs Delayed Erythropoiesis-Stimulating Agent Initiation in Nontransfusion-Dependent Patients With Lower-Risk MDS

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Final results from the phase III EPO-PRETAR study demonstrated no significant difference in time to RBC transfusion dependence with early vs delayed ESA initiation, although early ESA initiation increased erythroid response and prolonged duration of response compared with delayed ESA initiation in patients with lower-risk MDS and nontransfusion-dependent anemia.

Released: June 30, 2026

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Provided by Clinical Care Options, LLC dba Decera Clinical Education.

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Supporters

This activity is supported by educational grants from Incyte Corporation, Lilly, and Novartis Pharmaceuticals Corporation.

Incyte Corporation

Lilly

Novartis Pharmaceuticals Corporation

Target Audience

This activity is intended for hematologists, oncologists, and other healthcare professionals who care for patients with hematologic malignancies.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Integrate cutting-edge data from studies of hematologic malignancies at ASCO 2026 and EHA 2026 along with expert guidance to optimize personalized care and improve patient outcomes

  • Utilize prognostic and predictive biomarkers to accurately identify patients with hematologic malignancies most likely to benefit from specific targeted therapies and treatment strategies

  • Interpret newly released clinical data on novel agents, updated guidelines, and emerging therapeutic approaches for hematologic malignancies to accelerate their effective incorporation into clinical practice

  • Support informed shared decision-making for patients with hematologic malignancies through accessible discussion of the potential clinical implications of recently presented data at ASCO 2026 and EHA 2026