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ART Switch: How to Personalize

Clinical Thought

There are many ART switch options available for people living with virologically suppressed HIV who desire regimen simplification, decreased pill burden, or modernization. However, the specifics of patients’ treatment history, resistance profile, and comorbidities will affect which switch regimens are available to them, and these must be considered to determine available switch regimens before incorporating individual goals. Read on to learn what options are available and how to select among them.

Released: August 11, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

This activity is supported through an independent educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Merck & Co., Inc., Rahway, NJ, USA

Partners

Goldschmidt Collective

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Target Audience

This activity is intended for physicians, pharmacists, registered nurses, and other healthcare professionals who provide care for people living with HIV.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Guide clinical conversations to ascertain instances when patients may wish to switch a suppressive regimen 

  • Implement ART regimen switches in virologically suppressed individuals to support optimal long-term clinical outcomes

  • Apply emerging ART agents to expand the range of options for tailoring an optimal, individualized regimen for each person living with HIV

Financial Disclosures

Primary Author

Daniel Moring-Parris, MD, AAHIVS, has no relevant financial relationships to disclose.