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Persistent Barriers in Systemic Mastocytosis Care: How to Ensure Early Recognition, Diagnosis, and Treatment in Your Practice 

Clinical Thought

Barriers to timely systemic mastocytosis care persist despite growing awareness, emphasizing the need for early recognition of key signs and symptoms, appropriate diagnostic evaluation, and referral for confirmatory workup. Learn practical strategies for screening and individualizing treatment plans, while coordinating multidisciplinary care across specialties, to improve quality of life and clinical outcomes in patients with systemic mastocytosis.

Released: August 24, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by an educational grant from Blueprint Medicines Corporation.

Blueprint Medicines Corporation

Target Audience

This educational activity is intended for dermatology nurse practitioners and physician associates, other advanced practice providers, such as those practicing in primary care, who are engaged in the care of patients with SM.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Apply current consensus diagnostic frameworks—including clinical, laboratory, and pathologic criteria—to accurately identify systemic mastocytosis and determine disease subtype

  • Critically appraise emerging clinical evidence on targeted and disease-modifying therapies for systemic mastocytosis to support appropriate treatment selection and sequencing

Financial Disclosures

Primary Author

Carole Bitar, MD, FAAD: consultant/advisor/speaker/researcher: Arcutis.

Additional Disclosures

Generative artificial intelligence (AI) tools were used for revising or refining educational content. All AI-assisted content underwent human review, editing, and validation by qualified faculty and accredited education staff to ensure scientific accuracy, balance, and compliance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.