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Rising Serum Creatinine While on ART: What to Do

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This activity is available for 0.50 CME/CE credit(s).

Released: September 24, 2026

Expiration: September 23, 2027

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Some antiretroviral drugs (ARVs) are associated with nephrotoxicity, while others can cause low-level, early increases in creatinine, which may be mistaken for progressive decline in kidney function. Gain confidence distinguishing between these two scenarios with this AI-adaptive case, which leverages PRISM-ID, a Johns Hopkins–designed custom AI learning agent for HIV medicine. It features personalized, adaptive educational case scenarios. 

Rising Serum Creatinine While on ART

Pre Assessment: Prepare to Meet Your Patient

Assess your current knowledge and clinical approach before meeting your patient.
1.

How many people with HIV do you provide care for in a typical week?

2.

For those who practice in academic or community settings, please indicate your practice setting:

3.

In someone living with virologically suppressed HIV who takes DTG, 3TC, and TAF whose creatinine clearance drops to 28 mL/min, what additional test results would you review before switching to a tenofovir-sparing regimen?