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Potential Seroconversion on Long-Acting PrEP: Navigating the Possibilities

Case Challenge
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This activity is available for 0.50 CME/CE credit(s).

Released: September 02, 2026

Expiration: September 01, 2027

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Breakthrough HIV infection while on long-acting pre-exposure prophylaxis (PrEP) is very rare, but not unheard of. Learn how to navigate this possibility with this AI-adaptive case, which leverages PRISM-ID, a Johns Hopkins–designed custom AI learning agent for HIV medicine, which features personalized, adaptive educational case scenarios. 

Potential Seroconversion on PrEP

Pre Assessment: Prepare to Meet Your Patient

Assess your current knowledge and clinical approach before meeting your patient.
1.

How many people living with HIV do you provide care for in a typical week?

2.

For those who practice in academic or community settings, please indicate your practice setting:

3.

What would you recommend for a person who has HIV seroconversion and low-level viremia while receiving long-acting cabotegravir pre-exposure prophylaxis?