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MK-8591A-051 Wk 96: Switch From Standard-of-Care ART to DOR/ISL in People Living With Virologically Suppressed HIV

Conference Coverage
Slideset

In this Week 96 update from an open-label phase III clinical trial, switching from standard-of-care ART to DOR/ISL maintained a high rate of virologic suppression without treatment-emergent resistance or adverse effects on total lymphocyte or CD4+ cell counts and a favorable safety/tolerability profile.

Released: February 25, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by independent educational grants from Gilead Sciences, Inc., Merck & Co., Inc., Rahway, NJ, USA, and ViiV Healthcare.

Gilead Sciences, Inc.

Merck & Co., Inc., Rahway, NJ, USA

ViiV Healthcare

Target Audience

This activity is intended for physicians, pharmacists, registered nurses, and other healthcare professionals who care for people living with or at risk of HIV infection.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Appropriately apply and counsel patients regarding the clinical role(s) of new and investigational ART regimens and strategies

  • Devise HIV management strategies based on the results of recent clinical studies of established antiretroviral agents

  • Integrate the latest scientific findings to develop and optimize effective HIV prevention interventions