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nPEP Is Not the End: Lessons From London on the Transition to Rapid PrEP 

Clinical Thought

Nonoccupational postexposure prophylaxis (nPEP) should be considered an important entry point into ongoing HIV prevention. It is a way to prevent unnecessary gaps in HIV prevention for those with ongoing risk. Here, I discuss how to make the transition sufficiently streamlined so that patients do not need to navigate a second, potentially separate pathway to access PrEP.

Released: September 22, 2026

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Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by an educational grant from Gilead Sciences, Inc.

Gilead Sciences, Inc.

Target Audience

This activity is intended for physicians, pharmacists, registered nurses, and other healthcare professionals (both specialists and generalists) who provide PrEP.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Apply current IAS-USA and CDC guideline recommendations to determine when rapid or same-day PrEP is appropriate

  • Implement efficient, safe, and sustainable clinical workflows that support same day PrEP initiation across varied practice settings

  • Individualize the choice of PrEP modality—oral or long-acting injectable—during same day clinical encounters

Financial Disclosures

Primary Author

Gary Whitlock, MD, PhD: consultant/advisor/speaker: Gilead, ViV.