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Antiretroviral Therapy Initiation in the Setting of Opportunistic Infection

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This activity is available for 0.50 CME/CE credit(s).

Released: August 28, 2026

Expiration: August 27, 2027

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Starting antiretroviral therapy (ART) as soon as possible after a new HIV diagnosis is usually the standard of care, but advanced HIV infection with an AIDS-defining opportunistic infection (OI) is a distinct scenario that may require more nuanced timing. Learn which OIs should be treated before ART initiation and learn how to choose an initial ART regimen that accommodates OI treatment. It’s all in this AI-adaptive case, which leverages PRISM-ID, a Johns Hopkins–designed custom AI learning agent for HIV medicine. 

ART With Opportunistic Infection

Pre Assessment: Prepare to Meet Your Patient

Assess your current knowledge and clinical approach before meeting your patient.
1.

How many people living with HIV do you provide care for in a typical week?

2.

For those who practice in academic or community settings, please indicate your practice setting:

3.

In a person with advanced HIV and Pneumocystis jirovecii pneumonia (PJP), at what point should antiretroviral therapy (ART) be initiated?