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Managing Bispecific Antibody-Related Toxicities in Your Patients With Multiple Myeloma: Interdisciplinary Guidance and Care Coordination for Community HCPs

Slideset

These slides illustrate the expanding use of bispecific antibodies in relapsed/refractory multiple myeloma. The slide deck has visuals for toxicity management and REMS compliance. Other content in the deck includes key adverse event management issues, particularly CRS, ICANS, infection risk, and GPRC5D-associated on-target/off-tumor effects, and discuss evolving approaches, such as dexamethasone-first CRS management, prophylactic tocilizumab, infection prophylaxis, and outpatient or hybrid administration models. The goal is to improve safety and expand access across academic and community practice settings.

Released: August 18, 2026

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Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

This activity is supported by an educational grant from Johnson & Johnson.

Johnson & Johnson

Target Audience

This activity is intended for hematologists, oncologists, emergency medicine physicians, neurologists, infectious disease specialists, nurse practitioners, physician associates, nurses, pharmacists, and other healthcare professionals caring for patients with multiple myeloma who are eligible for or receiving bispecific antibody therapy.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Implement effective workflow processes to monitor and manage bispecific antibody–related toxicities in patients with MM using the latest evidence and expert-recommended strategies

  • Develop plans for coordinating care among different specialists, departments, and/or centers to optimize each patient’s therapeutic benefit from bispecific antibody therapy for MM

Additional Disclosures

Generative artificial intelligence (AI) tools were used for data analysis or summarization influencing content, and revising or refining educational content. All AI-assisted content underwent human review, editing, and validation by qualified faculty and accredited education staff to ensure scientific accuracy, balance, and compliance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education.