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Global Perspectives on ET and PV Diagnosis and Treatment

Clinical Thought

In this focused commentary, global experts discuss contemporary topics in the diagnosis and treatment of essential thrombocythemia (ET) and polycythemia vera (PV). 

Released: May 11, 2026

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Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by an educational grant from Merck Sharp & Dohme LLC.

Merck Sharp & Dohme, LLC

Target Audience

This activity is intended for hematologists and other healthcare professionals caring for patients with essential thrombocythemia and polycythemia vera.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Identify underlying MPNs such as ET and PV in patients presenting with thrombotic events that are otherwise unexplained

  • Diagnose patients with ET and PV, including bone marrow biopsies and assessment of risk of thrombotic events

  • Determine prognoses for individual patients with ET and PV using prognostic scoring system and identification of immune biomarkers

  • Engage patients with ET and PV in shared-decision making to better align treatment with both best practices and patient preferences on risks and benefits

  • Prepare clinical practice to incorporate new second-line agents for ET and PV upon approval

Disclosure

Primary Author

Ciro Rinaldi MD, PhD, has no relevant financial relationships to disclose.

Alessandro M. Vannucchi, MD: consultant/advisor/speaker: AbbVie, AOP Health, GSK, Italfarmaco, Menarini Stemline, Novartis; researcher (paid to institution): Ionctura.