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Second Line Agents for PBC
Second-line Agents for Achieving Treatment Goals: Raising the Bar in PBC Management Podcast

Released: December 11, 2025

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New therapeutic agents for second-line treatment are raising the bar for primary biliary cholangitis (PBC) management. Listen now to learn how to incorporate these new agents into clinical practice and how these agents will impact attainment of treatment goals.

Topics covered include:

  • Available agents for second-line treatment of PBC
  • An overview of clinical trial data supporting second-line agents:
    • Obeticholic acid (OCA)
    • Bezafibrate
    • Elafibranor
    • Seladelpar

This episode is the second of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode: https://bit.ly/4aL2ywX