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Precision Management of Colorectal Cancer With Biomarker Testing: An APP Perspective

Clinical Thought

Read this commentary for practical expert insights on integrating colorectal cancer biomarker testing into everyday oncology workflows, from initial MMR/MSI testing to actionable metastatic disease results.

Released: June 16, 2026

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Provided by

Provided by Partners for Advancing Clinical Education in partnership with Clinical Care Options, LLC dba Decera Clinical Education.

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Supporters

Supported by an educational grant from Pfizer Inc.

Pfizer, Inc.

Partners

Clinical Care Options, LLC dba Decera Clinical Education

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Target Audience

Nurse practitioners, physician associates, oncology nurses, and other healthcare professionals caring for patients with colorectal cancer.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Explain the clinical significance and implications of biomarker testing, including the role of germline and somatic mutations and their relevance in cancer care

  • Integrate evidence-based and best practice clinical care pathways to facilitate routine and rapid testing across tumor types

  • Interpret molecular profiling reports and biomarker testing results

  • Identify the role of advanced practice providers (APPs) in providing patient and family/care partner education on biomarker testing and treatment recommendations

  • Apply comprehensive communication and educational strategies to minimize health disparities and ensure biomarker testing use and accessibility in diverse patient populations

Faculty Disclosure

Primary Author

Ann Marie Siney, RN, MSN, ANP-BC, has no relevant financial relationships to disclose.