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MASTer Class in Systemic Mastocytosis: Expert Answers to Your Questions

Clinical Thought

Learn how to counsel patients with systemic mastocytosis (SM) about the chronic nature of their disease, what symptoms and red flags warrant a referral to allergy and immunology, and how SM is differentiated among other mast cell activation disorders in adult and pediatric patients.

Released: February 19, 2026

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Provided by Clinical Care Options, LLC dba Decera Clinical Education.

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Supporters

Supported by an educational grant from Blueprint Medicines, a Sanofi company.

Blueprint Medicines, a Sanofi company

Target Audience

This activity is intended for US-based physicians, including residents and fellows; physician associates; and nurse practitioners practicing in allergy/immunology and dermatology who care for patients with systemic mastocytosis. 

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Describe the pathogenesis, spectrum of clinical presentation, and differential diagnosis of SM

Disclosure

Primary Author

Benjamin Ungar, MD: consultant/advisor/speaker: AbbVie, Botanix, Bristol Myers Squibb, Ebla Holdco, Galderma, Johnson & Johnson, Leo Pharma, Lilly, Nektar, Pfizer, Sanofi, Veradermics, VRG Therapeutics.