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CE

My Approach to Suspected Systemic Mastocytosis in Allergy Practice

Clinical Thought

For advanced practice providers in allergy, learn how an expert approaches patient care for those suspected of having systemic mastocytosis, including physical evaluation, blood test interpretation, and when to refer for additional testing.

Physician Assistants/Physician Associates: 0.25 AAPA Category 1 CME credit

Nurse Practitioners/Nurses: 0.25 Nursing contact hour

Released: July 02, 2026

Expiration: July 01, 2027

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Faculty

Matthew P. Giannetti

Matthew P. Giannetti, MD

Associate Director of Brigham and Women’s Hospital Mastocytosis Center
Assistant Professor of Medicine, Harvard Medical School
Brigham and Women’s Hospital, Division of Allergy and Clinical Immunology
Boston, Massachusetts

Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by an educational grant from Blueprint Medicines Corporation.

Blueprint Medicines Corporation

Target Audience

This educational activity is intended for dermatology nurse practitioners and physician associates, other advanced practice providers, such as those practicing in primary care, who are engaged in the care of patients with SM.

Program Learning Goal

The goal of this educational activity is to improve the knowledge and competence of NP and PA learners in leveraging evidence-based, patient-centered care strategies to improve disease control and quality of life for patients with SM.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Explain the underlying biology and disease heterogeneity of systemic mastocytosis, including key pathogenic mechanisms, clinical phenotypes, and conditions that commonly mimic SM in practice

  • Apply current consensus diagnostic frameworks—including clinical, laboratory, and pathologic criteria—to accurately identify systemic mastocytosis and determine disease subtype

Financial Disclosures

Decera Clinical Education requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to Decera Clinical Education policy. Decera Clinical Education is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

Matthew P. Giannetti, MD: consultant/advisor/speaker: Blueprint, Cogen Biosciences, InmageneBio, NemaGen, Novartis, Palindrome.

The planners and content peer reviewers from Decera Clinical Education do not have any relevant financial relationships to disclose.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 0.25 hours. To successfully complete this activity and receive credit, participants must follow these steps during the period from July 02, 2026, through July 01, 2027:

  1. Login or Sign Up for an account by clicking at the top of this page.
  2. Read the target audience, learning objectives, and faculty disclosures.
  3. View and study the content in its entirety.
  4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.

Format

This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Additional Disclosures

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Accreditation

Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC dba Decera Clinical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 0.25 contact hours.

Physician Associate Continuing Medical Education 

Clinical Care Options, LLC dba Decera Clinical Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.25 AAPA Category 1 CME credits. Approval is valid until July 01, 2027. PAs should only claim credit commensurate with the extent of their participation.

IPCE Credit Designation

This activity was planned by and for the healthcare team, and learners will receive 0.25 Interprofessional Continuing Education (IPCE) credits for learning and change.