CE / CME
This interactive patient simulation series provides REMS-compliant CME/CE/CPE credits where learners gain a deep understanding of safe opioid practices and current guidelines. HCPs level up their knowledge in pain management, safe opioid prescribing, appropriate referral practices, patient education, and opioid use disorder to provide the highest level of personalized care to their patients, ensuring responsible opioid use in healthcare practices.
Nurse Practitioners/Nurses: 1.00 Nursing contact hour, including 1.00 hour of pharmacotherapy credit
Physician Assistants/Physician Associates: 1.00 AAPA Category 1 CME credit
Pharmacists: 1.00 contact hour (0.1 CEUs)
Physicians: maximum of 1.00 AMA PRA Category 1 Credit™
Released: December 05, 2025
Expiration: December 04, 2026
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Clinical Care Options (CCO), LLC, in partnership with Practicing Clinicians Exchange (PCE) and ProCE.
This activity is supported by an independent educational grant from the Opioid Analgesic REMS Program Companies.
Please see https://www.opioidanalgesicrems.com/Resources/Docs/List_of_RPC_Companies.pdf for a listing of REMS Program Companies. This activity is intended to be fully compliant with the Opioid Analgesic REMS education requirements issued by the U.S. Food and Drug Administration (FDA).
Opioid Analgesic REMS Program Companies
Practicing Clinicians Exchange
ProCE
The Opioid REMS interactive program is intended to reach interprofessional and multidisciplinary healthcare teams, including physicians, advanced practice nurses, physician associates, pharmacists, and nurses. Specialty areas include but are not limited to psychiatry, neurology, family medicine, internal medicine, pain management, physiatry, and surgery. This includes HCPs who are involved with direct patient care, including HCPs registered with the DEA and eligible to prescribe all opioid analgesics, as well as nonprescribers involved in the care of patients receiving opioid analgesic therapy, nonpharmacologic therapies, and nonopioid medication therapies.
Educate HCPs on safe prescribing practices for opioid medications, aiming to reduce the risk of addiction, misuse, overdose, and death by providing information on appropriate patient assessment, pain management strategies, and monitoring practices when prescribing opioids for pain treatment.
Upon completion of this activity, participants should be able to:
Differentiate the types of pain, including definitions, etiology, mechanisms, and risk factors
Identify risk factors for nonmedical use and opioid use disorder as part of a thorough assessment of pain and refer to addiction medicine specialists when appropriate
Develop individualized pain management plans considering all therapeutic options, including nonpharmacologic interventions, nonopioid medications, and opioid analgesics
Counsel patients and caregivers on the safe use, storage, and disposal of opioid analgesics and the role of reversal agents
Monitor patients receiving opioid therapy, including reviewing medication adherence, need for referral to pain specialist, potential for nonmedical use, and situations when it is appropriate to taper or discontinue opioid therapy
Construct a systematic approach to screening for and appropriately managing patients with opioid use disorder
Decera Clinical Education requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to Decera Clinical Education policy. Decera Clinical Education is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.
The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:
Primary AuthorMichael Sprintz, DO, DFASAM: consultant/advisor/speaker: Advanced Genomics Laboratory, Patch Technologies, Spark Biomedical, Tafalgie Therapeutics; individual publicly traded stock/stock options: Bridge Therapeutics.
Amanda Zimmerman, PA-C: consultant/advisor/speaker: Averitas.
The planners and content peer reviewers from Decera Clinical Education do not have any relevant financial relationships to disclose.
Participation in this self-study activity should be completed in approximately 1 hour. To successfully complete this activity and receive credit, participants must follow these steps during the period from December 05, 2025, through December 04, 2026:
You must receive a test score of at least and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.
This program has been made available online.
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC dba Decera Clinical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physician Continuing Medical Education
Clinical Care Options, LLC dba Decera Clinical Education designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nursing Continuing Professional Development
The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1 contact hour, including 1 hour of pharmacotherapy credit.
Continuing Pharmacy Education

Clinical Care Options, LLC dba Decera Clinical Education designates this continuing education activity for 1 contact hour (0.10 CEUs) of the Accreditation Council for Pharmacy Education. Universal Activity Number: JA4008176-0000-25-485-H01-P
Type of Activity: Knowledge
Upon successfully completing the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 60 days.
Physician Associate Continuing Medical Education

Clinical Care Options, LLC dba Decera Clinical Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1 AAPA Category 1 CME credit. Approval is valid until December 04, 2026. PAs should only claim credit commensurate with the extent of their participation.
IPCE Credit Designation

This activity was planned by and for the healthcare team, and learners will receive 1 Interprofessional Continuing Education (IPCE) credit for learning and change.

The CME credits that physicians earn from this activity will be submitted to ACCME's CME Passport, a free, centralized web application where you can create a personalized account to view, track, and generate transcripts of your reported CME credit. Visit www.cmepassport.org to create your account.