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Uncovering a Hidden Driver of Hypoparathyroidism: Improving ADH1 Detection and Cracking the Case With CaSR-Targeted Therapies (ENDO)

ADH1 is a rare but clinically significant disorder caused by calcium-sensing receptor (CaSR) variants and leading to calcium dysregulation, hypoparathyroidism, and risks to renal health. This program covers ADH1 pathophysiology, presentation, genetic testing, available and emerging treatment approaches, and patient experiences to increase HCPs’ confidence in diagnosing and managing ADH1 and improving long-term patient outcomes.

This independent, supported Satellite Symposia is not part of the ENDO 2026 official educational programming as planned by the Endocrine Society Annual Meeting Steering Committee. This program is neither sponsored nor endorsed by the Endocrine Society. The information presented here has not been reviewed or approved by the Endocrine Society for accuracy or completeness, and the views expressed in this presentation are those of the presenters and do not represent the views of the Endocrine Society. This program may offer continuing medical education (CME) or MOC credit provided by the sponsoring organization.

Physicians: maximum of 1.00 AMA PRA Category 1 Credit

Physician Assistants/Physician Associates: 1.00 AAPA Category 1 CME credit

Nurse Practitioners/Nurses: 1.00 Nursing contact hour

Who Should Attend

This activity is designed for clinicians involved in the management of patients with ADH1, including endocrinologists, nephrologists, primary care physicians, orthopedists, nurse practitioners, physician associates, and other members of the care team. 

Time and location

Sunday, June 14, 2026

6:30 AM - 8:00 AM Central Time (CT)

In-person

7:00 AM - 8:00 AM Central Time (CT)

Virtual

Hyatt Regency McCormick Place
2233 S Dr Martin Luther King Jr Drive
Chicago, Illinois 60616

Regency Ballroom CDE - 2nd Floor

Agenda

  • Welcome and Introductions
  • The Case of the Missing Diagnosis: Identifying ADH1 as the Hidden Culprit in Hypoparathyroidism and the CaSR Biology Behind the Clues
  • Following the Genetic Trail: Using Genetic Testing to Confirm the Suspect
  • Cracking the Calcium Code: Targeting the Root Cause to Restore Balance

Location

Venue Name

Hyatt Regency McCormick Place

Address

Hyatt Regency McCormick Place
2233 S Dr Martin Luther King Jr Drive
Chicago, Illinois 60616

Room Name

Regency Ballroom CDE - 2nd Floor

CME/CE Info

Goal Statement
The goal of this activity is to improve learners’ knowledge, competence, and performance in evidence-based management of patients with ADH1. 

Target Audience
This activity is designed for clinicians involved in the management of patients with ADH1, including endocrinologists, nephrologists, primary care physicians, orthopedists, nurse practitioners, physician associates, and other members of the care team. 

Learning Objectives
Upon completion of this event, participants should be able to:

  • Identify ADH1 as an underrecognized cause of hypoparathyroidism by recognizing clinical features that raise suspicion for the diagnosis. 
  • Understand the activating mutations in the calcium-sensing receptor (CaSR) gene that underlie ADH1.
  • Apply genetic testing strategies for suspected ADH1, including appropriate test selection, result interpretation, and consideration of access and ethical implications, to confirm diagnosis and inform clinical management
  • Evaluate emerging clinical trial evidence for novel therapeutic approaches that target the underlying causes of ADH1, including CaSR-targeted therapies, to optimize calcium homeostasis and reduce renal complications

Accreditation

Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by Clinical Care Options, LLC dba Decera Clinical Education and the HypoPARAthyroidism Association, Inc. Clinical Care Options, LLC dba Decera Clinical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

Clinical Care Options, LLC dba Decera Clinical Education designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1.0 contact hour.

Physician Associate Continuing Medical Education

Clinical Care Options, LLC dba Decera Clinical Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit. PAs should only claim commensurate with the extent of their participation.

IPCE Credit Designation

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This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credit for learning and change.

CME Passport

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The CME credits that physicians earn from this activity will be submitted to ACCME's CME Passport, a free, centralized web application where you can create a personalized account to view, track, and generate transcripts of your reported CME credit. Visit www.cmepassport.org to create your account.

Disclosure of Conflicts of Interest
Decera Clinical Education requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to Decera Clinical Education policy. Decera Clinical Education is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

Acknowledgement

Provided by

Provided by Clinical Care Options, LLC dba Decera Clinical Education in partnership with HypoPARAthyroidism Association, Inc.

Clinical Care Options, LLC dba Decera Clinical Education

Supporter

This activity is supported by an independent educational grant from BridgeBio Pharma, Inc.

BridgeBio Pharma, Inc.

Partner

HypoPARAthyroidism Association, Inc

HypoPARAthyroidism Association, Inc

Contact Information

For customer support please click here.

Mailing Address:

 

Decera Clinical
12001 Sunrise Valley Drive
Suite 304
Reston, VA 20191

Additional Information

There are no fees required to participate in this activity.

Americans With Disabilities Act 
Event staff will be glad to assist you with any special needs (eg, physical, dietary). Please contact customer support prior to the live event.